Purpura fulminans secondary to indian tick typhus: a case report
Keywords:Purpura fulminans, Rickettsia, Indian tick typhus, Retiform purpura, Gangrene
Purpura fulminans is a rare and commonly fatal syndrome that consists of hemorrhagic infarction of the skin and intravascular thrombosis. Purpura fulminans is commonly associated with streptococcal, staphylococcal and meningococcal infection. Indian tick typhus is a rare cause of purpura fulminans. One of the rare causes of purpura fulminans is Indian tick typhus, which is a type of rickettsial spotted fever caused by Rickettsia conorii and transmitted to humans by Rhipicephalus sanguineus (also called the dog tick). Clinical features of Indian tick typhus include fever, maculopapular rash that begins on the extremities with a centripetal spread, and constitutional symptoms including headache, malaise and conjunctival congestion. Severe cases can progress to multi-organ disease including pulmonary edema, meningoencephalitis, renal failure and cardiogenic shock can occur. Current report present a case of a 48 year old male patient who presented with features of Indian tick typhus which progressed to purpura fulminans and necrotizing fasciitis.
Dalugama C, Gawarammana IB. Rare presentation of rickettsial infection as purpura fulminans: a case report. J Med Case Rep. 2018;12(1):145.
Biradar S, Holyachi R, Kadeli DK. Purpura fulminans secondary to rickettsial infection: a case report. J Clin Diagn Res. 2015;(11):1-2.
Hulmani M, Alekya P, Kumar VJ. Indian tick typhus presenting as purpura fulminans with review on rickettsial infections. Indian J Dermatol. 2017;62: 1 6.
Katoch S, Kallappa R, Shamanur MB, Gandhi S. Purpura fulminans secondary to rickettsial infections: A case series. Indian Dermatol J. 2016;7:24-8.
Kumar M, Singh R, Yadav M. Indian tick typhus presenting with gangrene: a case report from an urban slum of Delhi. Indian J Pediatr. 2014;81(1):95-7.
Sharma A, Mishra B. Rickettsial disease existence in India: resurgence in outbreaks with the advent of 20th century. Indian J Health Sci Biomed Res. 2020;13:5-10.