Langerhans cell histiocytosis in an infant: a case report from North-East India

Authors

  • Romita Bachaspatimayum Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India
  • Kago Yaku Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20204569

Keywords:

Children, Cutaneous manifestations, LCH

Abstract

Langerhans cell histiocytosis (LCH) is a rare disorder of reticuloendothelial system characterized by uncontrolled proliferation and accumulation of CD1a and CD207 dendritic cells (DCs). 3-4 cases per million occur annually in children under 15 years of age, with a male:female ratio of 2:1 and peak incidence in infants aged 1 to 2 years. Report a case of LCH in a month-old female infant with skin lesions for 2-3 weeks. Skin biopsy was suggestive of LCH and it was confirmed with immunohistochemistry markers that were positive for S100, CD1A and negative for CD68.

 

Author Biography

Kago Yaku, Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India

Post graduate Trainee, Department of Dermatology, Venereology and leprology

References

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Published

2020-10-22