A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

Authors

  • Eby Chacko Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India
  • Seethalakshmi Ganga Vellaisamy Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India
  • Kannan Gopalan Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India
  • Govindarajan Nanjappachetty Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20170798

Keywords:

Polymorphic light eruption, Clinico-epidemiological study, Photodermatosis, South India

Abstract

 Introduction: Polymorphic light eruption (PMLE) is an acquired photodermatosis characterized by a polymorphic eruption ranging from papulovesicular lesions to large plaques. The prevalence of PMLE varies from 5% to 15% in various studies across the world and in India it is 0.56%.

Objective: The present study was conducted to study the clinical pattern and to assess the epidemiological aspects of polymorphic light eruption.

Material and Method: A cross sectional prospective study was conducted in Dermatology OPD between April 2015 and June 2016. A total of 100 patients with symptoms and signs of PMLE were included in the study. Data were coded and analyzed.

Results: Majority of the cases in our study were in the age group of 21 - 30 years (36%). It was more common in females (82%) when compared with males (18%). Occupation of most of the patients (29%) was farmers in our study population. Positive family history of PMLE was seen in 11% of the study population. The commonest form was the papular type (46%) and the second most common type was plaque type (17%). Regarding the distribution of lesions, about  51%  of  our study subjects had polymorphic lesions confined to only one area of their body mostly forearm (25%) followed by face (12%).

Conclusion: The prevalence of PMLE was 1.34% in our study population. Pruritus was the presenting complaint in most of the cases and the rash was mainly seen in areas exposed to sunlight.

Author Biographies

Eby Chacko, Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India

Postgraduate student, Department of Skin & STD

Seethalakshmi Ganga Vellaisamy, Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India

Assistant Professor, Department of Skin & STD

Kannan Gopalan, Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India

Professor & HOD, Department of Skin & STD

Govindarajan Nanjappachetty, Department of Skin and STD, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu – 636308, India

Professor, Department of Skin & STD

References

Norris PG, Barker JN, Allen MH, et al. Adhesion molecule expression in polumorphic light eruption. J Invest Dermatol. 1992;99(4):504-8.

Ros AM, Wennersten G. Current aspects of polymorphous light eruption in Sweden. Photodermatology. 1986;3(5):298–302.

Pao C, Norris PG, Corbett M, Hawk JL. Polymorphic light eruption: prevalence in Australia and England. Br J Dermatol. 1994;130(1):62–4.

Morison WL, Stern RS. Polymorphous light eruption: a common reaction uncommonly recognized. Acta Derm Venereol (Stockh). 1982;62(3):237–40.

Khoo SW, Tay YK, Tham SN. Photodermatoses in a Singapore skin referral center. Clin Exp Dermatol. 1996;21(4):263–8.

Sharma L, Basnet A. A clinic epidemiological study of PMLE. Indian J Dermatol Venerol Leprol. 2008;74:15-7.

Fitzpatrick TB. The validity and practicality of sun reactive skin type I through VI. Arch Dermatol. 1988;124:869.

Prasad P, Kaviarasan PK, Udhay S. A Clinico-pathological Study of PMLE. Journal of Cosmetics, Dermatological Sciences and Applications. 2012;2:219-23.

Jansen CT, Darvonen J. Polymorphous light eruption. A seven year follow up evaluation of 114 patients. Arch Dermatol. 1984;120:862.

Boonstra HE, van Weelden H, Toonstra J, van Vloten WA. Polymorphous light eruption: a clinical, photobiologic, and follow-up study of 110 patients. J Am Acad Dermatol. 2000;42:199–207.

Aubin F. Why Is Polymorphous Light Eruption so Common in Young Women. Archives of Dermatological Research. 2004;296(5):240-1.

Berg M. Epidemiological Studies of the Influence of Sun Light on the Skin. Photo-dermatology. 1989;6(2):80-5.

Tutrone WD, Spann CT, Scheinfeld N, Delevo VA. Dermatologic therapy. 2003;16(1):28-39.

Dermatologic Disease Database: Polymorphic light eruption: http://www.aocd.org/skin/dermatologic-disease/polymorphous-lighteruption.htm. Accessed 15 November 2016.

Morrison et al. The New England J Med. 2004;350(11):1111.

Sophie Shirin et al. Global Dermatology – Polymorphous light eruption. Sept 27, 2005. P 1. www.emedicine.com/derm/topic342.htm. Accessed 15 November 2016.

Hawk JLM, Norris PG. Abnormal response to ultraviolet radiation: idiopathic. In: Irwin MF et al. Eds. Fitzpatrick’s Dermatology in General Medicine. 5th edition. New York: Mc-Graw Hill; 1999: 1573-1589.

Naleway AL. Polymorphous light eruption. Int J Dermatol. 2002;41:377–83.

Bansal I, Kerr H, Janiga JJ, Quershi MS. Pin-point Papular Variant of Polymorphous Light Eruption: Clinical and Pathological Correlation. Journal of the European Academy of Dermatology and Venereology. 2006;20(4):406-11.

McGregor JM, Grabezynska S, Vaughan R. Ge-netic Modeling of Abnormal Photo Sensivity in Families with Polymorphic Light Eruption and Actinic Prurigo. Journal of Investigative Dermatology. 2000;115:471-6.

Millard TP, Bataille V, Snieder H. The Heritabil-ity of Polymorphic Light Eruption. Journal of Investiga-tive Dermatology. 2000;115:467-70.

Orr PH, Birt AR. Hereditary polymorphic light eruption in Canadian unit. Int J Dermatol. 1984;23(7):472-5.

Jansen CT. The natural history of polymorphous light eruptions. Arch Dermatol. 1979;115(2):165–9.

Mastalier U, Kerl H, Wolf P. Clinical, laboratory, phototest and phototherapy findings in polymorphic light eruptions: a retrospective study of 133 patients. Eur J Dermatol. 1998;8:554–9.

John LM, Hawk. The photosensitivity disorders. 8th edition.1997; 305-310.

John LM, Hawk. Abnormal responses to ultraviolet radiation: Idiopathic, probably immunologic and photo exacerbated. In: Irwin MF et al. Eds. Fitzpatrick’s Dermatology in General Medicine 6th Edn. New York: Mc-Graw Hill; 2003: 1283.

Reinhard. Clinical and therapeutic aspects of polymorphous light eruption. Dept of Dermatology, University Hospital, Zurich, Switzerland. Dermatology. 2003;207:93-5.

Lamb et al. Solar Dermatitis. Arch Derm. 1957; 75: 171-180.

Kontos AP, Cusack CA, Chaffins M, Lim HW. Polymorphous light eruption in African Americans: Pinpoint popular variant. Photodermatol Photoimmunol Photomed. 2002;18(6):303-6.

Guarrera M, Micallizi C, Rebora A. Heterogeneity of polymorphic light eruption: A study of 105 patients. Arch Dermatol. 1993;129:1060-2.

Gonzalez E, Gonzalez S. Drug photosensitivity, idiopathic photodermatosis and sunscreens. J Am Acad Dermatol. 1996;35:871-85.

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Published

2017-02-23

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